Application 01
Two-Photon Microscopy
Two-photon microscopy enables deep-tissue imaging with cellular resolution in living organisms. It depends critically on a pulsed near-infrared source with high peak power and high repetition rate — exactly what the HUMMINGBIRD-1030 delivers in a form small enough to mount on a microscope head.
- Deep-tissue imaging up to 1 mm in scattering media
- Reduced photobleaching vs. single-photon methods
- Live cell and in vivo brain imaging
- FLIM (Fluorescence Lifetime Imaging Microscopy)
- Calcium imaging for neuronal circuit mapping
Application 02
Ophthalmology
Femtosecond lasers have transformed refractive and cataract surgery. Their ultra-short pulses enable photodisruption of ocular tissue with sub-micron precision and no collateral thermal damage — critical in delicate ophthalmic procedures.
- LASIK — precise, reproducible corneal flap creation
- SMILE — lenticule cutting for flapless refractive correction
- FLACS — capsulotomy and lens fragmentation for cataract surgery
- Corneal collagen cross-linking activation
- Intrastromal corneal ring segment (ICRS) tunneling
Application 03
Two-Photon Polymerization
Two-photon polymerization (2PP) is the gold standard for true 3D nanoscale fabrication. By focusing femtosecond pulses into a photosensitive resin, structures can be written with feature sizes well below the diffraction limit — enabling nanoscale printing of complex 3D objects.
- 3D nano- and micro-structure fabrication
- Photonic crystal and waveguide writing
- Microfluidic device prototyping
- Scaffold fabrication for tissue engineering
- MEMS and micro-optics production
- Metamaterial fabrication
Application 04
Precision Micromachining
Femtosecond "cold ablation" uses extreme peak intensity to remove material through direct ionization — not thermal melting. The result is clean, precise cuts with near-zero heat-affected zone in virtually any material. The PEREGRINE amplifier series provides the higher pulse energies required for efficient material removal.
- Drilling — sub-micron holes in metals, ceramics, and glass
- Cutting — glass, wafers, thin films, and composites
- Surface texturing — anti-reflective and hydrophobic structures
- Waveguide writing — direct inscription in glass
- Medical device stent cutting
- MEMS fabrication and repair
Application 05
LIBS Spectroscopy
Laser-Induced Breakdown Spectroscopy (LIBS) creates a plasma from a sample surface and analyzes the emitted light for elemental composition. Femtosecond LIBS offers reduced matrix effects, improved precision, and better depth resolution compared to nanosecond systems.
- Elemental analysis of metals, minerals, and biological samples
- Depth profiling with nanometer resolution per shot
- Stand-off detection and remote sensing
- Cultural heritage — non-destructive art conservation
- Environmental monitoring and contamination detection
Application 06
Seed Laser for Amplified Systems
High-power femtosecond amplifiers (CPA, fiber, OPA) require a stable, low-noise seed oscillator. The seed determines the pulse properties that will be amplified downstream. The HUMMINGBIRD-1030 provides transform-limited pulses with a digital clock output for synchronization — an ideal seed source.
- Seed for Ti:Sapphire CPA amplifiers
- Seed for Yb-fiber CPA amplifiers
- OPA/OPCPA pump seeding
- Synchronization via digital clock output
- Low timing jitter for pump-probe experiments
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